One night driving home from work, I was telling my son about this crazy 22 thing. When we arrived home, the Simpsons was on TV. It's the episode where Lisa gets on the #22 bus. However, it turns out to be the wrong bus. She asks the driver about it, and he explains that there are actually two #22 buses, the 22A which runs Monday, Wednesday, Friday, and the 22B on the other days.